Across TCGA patient cohorts, NHLRC3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,161 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NHLRC3-associated genes across cancer lineages are ZWINT, SGO1, and KIF11. Each is linked with NHLRC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NHLRC3-to-partner and partner-to-NHLRC3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC3→partner) and Y-score (partner→NHLRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZWINT →	-0.646	-0.343	.001	<.001	3	4
LUAD	SGO1 →	-0.608	-0.433	.001	<.001	3	4
BRCA	KIF11 →	-0.781	-0.369	<.001	<.001	3	4
BRCA	KIF20B →	-0.585	-0.316	.001	.002	3	4
LSCC	DNA2 →	-0.528	-0.223	.004	<.001	3	4
BRCA	ORC1 →	-0.664	-0.310	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,161 associations by consensus.

Exploration

NHLRC3 survival (RNA) · tumor vs normal (RNA) · all NHLRC3 data types