NGRN

Across TCGA patient cohorts, NGRN protein abundance is significantly associated with the protein abundance of many other proteins, with 9,150 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NGRN-associated proteins across cancer lineages are MRPL9, MRPL1, and MRPL17. Each is linked with NGRN in more than 5 cancer types. Because this analysis shows association rather than direction, both NGRN-to-partner and partner-to-NGRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NGRN versus MRPL9 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NGRN→partner) and Y-score (partner→NGRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MRPL9 →	+0.411	+0.409	<.001	<.001	3	6
LUAD	MRPL1 →	+0.378	+0.255	<.001	<.001	3	6
PDAC	MRPL17 →	+0.459	+0.535	<.001	<.001	3	6
BRCA	MRPL46 →	+0.393	+0.460	<.001	<.001	3	6
CCRCC	MALSU1 →	+0.478	+0.352	<.001	<.001	3	6
LSCC	ERAL1 →	+0.630	+0.419	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,150 associations by consensus.

NGRN vs MRPL9 — LUAD

Explore this scatter interactively →