NFX1

Across TCGA patient cohorts, NFX1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,366 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NFX1-associated genes across cancer lineages are CHMP5, APTX, and DCAF12. Each is linked with NFX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NFX1-to-partner and partner-to-NFX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFX1 versus CHMP5 in HNSC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFX1→partner) and Y-score (partner→NFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CHMP5 →	+0.732	+0.170	<.001	.002	3	5
LSCC	APTX →	+0.529	+0.209	<.001	<.001	3	5
HNSC	DCAF12 →	+0.677	+0.221	<.001	<.001	3	5
HNSC	EBLN3P →	+0.637	+0.192	<.001	<.001	3	5
OV	VCP →	+0.631	+0.517	.002	.004	3	4
HNSC	UBE2R2 →	+0.657	+0.238	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,366 associations by consensus.

NFX1 vs CHMP5 — HNSC

Explore this scatter interactively →