NFX1

Across TCGA cell cohorts, NFX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,391 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFX1-associated GO terms across cancer lineages are tRNA export from nucleus, tRNA transport, and Protein sumoylation. Each is linked with NFX1 in more than 15 cancer types. Because this analysis shows association rather than direction, both NFX1-to-partner and partner-to-NFX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA export from nucleus grouped by NFX1-low versus NFX1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFX1→partner) and Y-score (partner→NFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	tRNA export from nucleus →	+0.158	+0.893	<.001	<.001	3	16
CNS	tRNA transport →	+0.128	+0.503	<.001	.001	3	15
SOFT_TISSUE	Protein sumoylation →	+0.072	+0.710	<.001	<.001	3	13
KIDNEY	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.067	+0.801	.002	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.088	+0.956	<.001	.002	3	12
URINARY_TRACT	Regulation of chromatin organization →	+0.077	+0.602	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,391 associations by consensus.

tRNA export from nucleus by NFX1 expression — PANCREAS

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