NFU1

Across TCGA pan-cancer cohorts, NFU1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NFU1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NFU1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NFU1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where NFU1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.885	.018	24	view →
CCRCC	DFS	Median	II,III,IV	0.473	0.764	.008	15	view →
PDAC	OS	Median	All	0.461	0.284	.007	13	view →
LSCC	DFS	Median	II,III,IV	1.000	0.836	.005	8	view →
LUAD	DFS	Tertile	All	0.526	0.782	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NFU1–COAD (DFS)

Open the COAD breakdown →