NFRKB

Across TCGA cell cohorts, NFRKB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,750 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NFRKB-associated GO terms across cancer lineages are Meiotic chromosome condensation, Epigenetic regulation of gene expression, and Signal transduction in response to DNA damage. Each is linked with NFRKB in more than 16 cancer types. Because this analysis shows association rather than direction, both NFRKB-to-partner and partner-to-NFRKB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by NFRKB-low versus NFRKB-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFRKB→partner) and Y-score (partner→NFRKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Meiotic chromosome condensation →	+0.165	+0.719	<.001	<.001	3	17
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.060	+1.058	<.001	<.001	3	15
BONE	Signal transduction in response to DNA damage →	+0.072	+0.828	.006	<.001	3	14
STOMACH	Negative regulation of gene expression, epigenetic →	+0.060	+0.600	.008	.005	3	14
BONE	DNA integrity checkpoint signaling →	+0.101	+0.865	<.001	<.001	3	14
OESOPHAGUS	Copper ion export →	-0.211	-1.063	.003	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,750 associations by consensus.

Meiotic chromosome condensation by NFRKB expression — CNS

Explore this box plot interactively →