NFKBIB

Across TCGA cell cohorts, NFKBIB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,589 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFKBIB-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Regulation of DNA-templated DNA replication, and Metaphase/anaphase transition of cell cycle. Each is linked with NFKBIB in more than 12 cancer types. Because this analysis shows association rather than direction, both NFKBIB-to-partner and partner-to-NFKBIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by NFKBIB-low versus NFKBIB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIB→partner) and Y-score (partner→NFKBIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.173	+0.880	<.001	.003	3	13
BLOOD_Myeloma	Regulation of DNA-templated DNA replication →	+0.100	+1.033	.001	.001	3	12
BONE	Metaphase/anaphase transition of cell cycle →	+0.166	+0.824	<.001	<.001	3	11
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.135	+0.811	<.001	<.001	3	11
BLOOD_Lymphoma	Peptidyl-proline modification →	+0.096	+0.938	<.001	<.001	3	11
BONE	U2-type prespliceosome assembly →	+0.118	+1.054	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,589 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by NFKBIB expression — BONE

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