NFKBIA

Across TCGA patient cohorts, NFKBIA protein abundance is significantly associated with the RNA expression of many other genes, with 8,581 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NFKBIA-associated genes across cancer lineages are GMPR2, HOMEZ, and BUB1B. Each is linked with NFKBIA in more than 4 cancer types. Because this analysis shows association rather than direction, both NFKBIA-to-partner and partner-to-NFKBIA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFKBIA versus GMPR2 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIA→partner) and Y-score (partner→NFKBIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GMPR2 →	+0.373	+0.241	.003	.004	3	5
CCRCC	HOMEZ →	+0.488	+0.304	<.001	<.001	3	4
CCRCC	BUB1B →	-0.744	-0.210	<.001	.004	3	4
CCRCC	MAD2L1 →	-0.664	-0.236	<.001	<.001	3	4
LUAD	AP4S1 →	+0.498	+0.356	<.001	<.001	3	3
PDAC	VCPKMT →	+0.293	+0.642	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,581 associations by consensus.

NFKBIA vs GMPR2 — BRCA

Explore this scatter interactively →