NFIB

Across TCGA cell cohorts, NFIB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,195 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NFIB-associated GO terms across cancer lineages are Multi-ciliated epithelial cell differentiation, Regulation of epithelial cell proliferation involved in lung morphogenesis, and Cell proliferation in forebrain. Each is linked with NFIB in more than 10 cancer types. Because this analysis shows association rather than direction, both NFIB-to-partner and partner-to-NFIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-ciliated epithelial cell differentiation grouped by NFIB-low versus NFIB-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFIB→partner) and Y-score (partner→NFIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Multi-ciliated epithelial cell differentiation →	+0.151	+1.867	<.001	<.001	3	11
LIVER	Regulation of epithelial cell proliferation involved in lung morphogenesis →	-0.235	-2.101	.001	.001	3	11
SOFT_TISSUE	Cell proliferation in forebrain →	+0.112	+1.960	<.001	<.001	3	9
SOFT_TISSUE	Neural precursor cell proliferation →	+0.073	+1.900	<.001	<.001	3	8
SOFT_TISSUE	Multi-organism reproductive process →	-0.077	-2.316	.002	<.001	3	7
LARGE_INTESTINE	Negative regulation of cell activation →	-0.069	-1.302	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,195 associations by consensus.

Multi-ciliated epithelial cell differentiation by NFIB expression — SOFT_TISSUE

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