Across TCGA cell cohorts, NF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NF1-associated GO terms across cancer lineages are Nucleic acid transport, RNA transport, and Positive regulation of mRNA metabolic process. Each is linked with NF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NF1-to-partner and partner-to-NF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NF1→partner) and Y-score (partner→NF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nucleic acid transport →	+0.097	+0.831	<.001	<.001	3	17
SOFT_TISSUE	RNA transport →	+0.097	+0.831	<.001	<.001	3	17
STOMACH	Positive regulation of mRNA metabolic process →	+0.096	+1.309	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of organelle assembly →	+0.075	+0.892	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleotide-excision repair →	+0.123	+1.319	<.001	<.001	3	16
SOFT_TISSUE	Establishment of RNA localization →	+0.097	+0.811	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,882 associations by consensus.

Exploration

NF1 survival (RNA) · tumor vs normal (RNA) · all NF1 data types