NEUROG3

Across TCGA patient cohorts, NEUROG3 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEUROG3-associated genes across cancer lineages are eEF2, ERK2, and Fibronectin. Each is linked with NEUROG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEUROG3-to-partner and partner-to-NEUROG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by NEUROG3-low versus NEUROG3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROG3→partner) and Y-score (partner→NEUROG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.431	+2.000	.007	.032	3	1
UCEC	ERK2 →	+0.233	+2.000	.007	.032	3	1
UCEC	Fibronectin →	-0.309	-2.000	.038	.032	3	1
UCEC	GAPDH →	+0.534	+3.000	.027	.036	3	1
UCEC	MEK1 →	+0.412	+2.000	.012	.032	3	1
UCEC	mTOR_pS2448 →	-0.187	-2.986	.005	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

eEF2 by NEUROG3 expression — UCEC

Explore this box plot interactively →