NEUROG3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NEUROG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 344 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NEUROG3-associated GO terms across cancer lineages are Endosomal transport, Positive regulation of lymphocyte migration, and Protein localization to vacuole. Each is linked with NEUROG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEUROG3-to-partner and partner-to-NEUROG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by NEUROG3-low versus NEUROG3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROG3→partner) and Y-score (partner→NEUROG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCEndosomal transport →+0.041+1.046<.001.00833
LUNG_SCLCPositive regulation of lymphocyte migration →-0.093-1.191<.001.00233
LUNG_SCLCProtein localization to vacuole →+0.086+2.045<.001.00333
OVARYResponse to endoplasmic reticulum stress →+0.048+0.020.003.00723
LUNG_NSCLC_LUADNeural tube development →+0.045+0.018.008.00632
LUNG_SCLCIcosanoid secretion →-0.098-1.547.003.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 344 associations by consensus.

Endosomal transport by NEUROG3 expression — LUNG_SCLC

Box plot of Endosomal transport in NEUROG3-low vs NEUROG3-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration