NEUROD6

Across TCGA patient cohorts, NEUROD6 mutation is significantly associated with the RNA expression of many other genes, with 1,602 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEUROD6-associated genes across cancer lineages are TIPIN, MIR6853, and NPM1P45. Each is linked with NEUROD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEUROD6-to-partner and partner-to-NEUROD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIPIN grouped by NEUROD6-low versus NEUROD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD6→partner) and Y-score (partner→NEUROD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.555	+3.413	<.001	<.001	3	3
BRCA	MIR6853 →	+0.145	+7.057	<.001	.009	3	2
LIHC	NPM1P45 →	+0.092	+5.758	<.001	.003	3	2
CESC	RN7SL658P →	+0.086	+4.144	<.001	.009	3	2
CESC	MIR615 →	+0.866	+3.413	<.001	.006	3	2
LUAD	RN7SKP3 →	+0.218	+4.502	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,602 associations by consensus.

TIPIN by NEUROD6 expression — UCEC

Explore this box plot interactively →