NEUROD6

Across TCGA cell cohorts, NEUROD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,874 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEUROD6-associated GO terms across cancer lineages are Negative regulation of cell activation, Actin crosslink formation, and Skeletal myofibril assembly. Each is linked with NEUROD6 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEUROD6-to-partner and partner-to-NEUROD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell activation grouped by NEUROD6-low versus NEUROD6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD6→partner) and Y-score (partner→NEUROD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell activation →	-0.067	-3.698	<.001	<.001	3	4
BONE	Actin crosslink formation →	-0.177	-3.048	<.001	.001	2	4
LUNG_SCLC	Skeletal myofibril assembly →	-0.869	-1.539	<.001	.002	3	3
LUNG_SCLC	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	-0.650	-1.796	<.001	.002	3	3
BONE	Protein targeting to vacuole involved in autophagy →	-0.187	-3.849	<.001	<.001	3	3
BONE	Negative regulation of protein phosphorylation →	-0.047	-2.885	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,874 associations by consensus.

Negative regulation of cell activation by NEUROD6 expression — BONE

Explore this box plot interactively →