NEUROD6

Across TCGA cell cohorts, NEUROD6 mutation is significantly associated with the mutation status of many other genes, with 4,264 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NEUROD6-associated genes across cancer lineages are TRPV6, KSR1, and TGM1. Each is linked with NEUROD6 in more than 4 cancer types. Because this analysis shows association rather than direction, both NEUROD6-to-partner and partner-to-NEUROD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRPV6 grouped by NEUROD6-low versus NEUROD6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD6→partner) and Y-score (partner→NEUROD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TRPV6 →	+5.584	+5.014	.003	.003	1	5
OVARY	KSR1 →	+5.415	+5.415	.004	.004	1	5
BREAST	TGM1 →	+4.297	+4.857	.009	.009	1	4
CNS	POLE →	+3.862	+4.347	.001	.001	1	4
BLOOD_Lymphoma	SVEP1 →	+2.710	+4.203	.008	.008	1	4
BLOOD_Lymphoma	IPO7 →	+4.584	+4.584	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,264 associations by consensus.

TRPV6 by NEUROD6 expression — BLOOD_Lymphoma

Explore this box plot interactively →