NEUROD4

Across TCGA cell cohorts, NEUROD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 208 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NEUROD4-associated GO terms across cancer lineages are Galactolipid biosynthetic process, Regulation of CD8-positive, alpha-beta T cell proliferation, and Regulation of interleukin-1 production. Each is linked with NEUROD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEUROD4-to-partner and partner-to-NEUROD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Galactolipid biosynthetic process grouped by NEUROD4-low versus NEUROD4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD4→partner) and Y-score (partner→NEUROD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Galactolipid biosynthetic process →	+0.734	+2.158	.004	.001	3	2
LUNG_SCLC	Regulation of CD8-positive, alpha-beta T cell proliferation →	-0.169	-2.774	<.001	<.001	3	2
LUNG_SCLC	Regulation of interleukin-1 production →	-0.082	-1.965	<.001	.002	3	2
LUNG_SCLC	Negative regulation of growth →	-0.035	-1.782	.002	.003	3	2
LUNG_SCLC	Blood vessel morphogenesis →	-0.036	-1.786	.001	.001	3	2
LUNG_SCLC	Galactosylceramide biosynthetic process →	+0.734	+2.158	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 208 associations by consensus.

Galactolipid biosynthetic process by NEUROD4 expression — LUNG_SCLC

Explore this box plot interactively →