NEUROD1

Across TCGA patient cohorts, NEUROD1 mutation is significantly associated with the RNA expression of many other genes, with 1,114 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEUROD1-associated genes across cancer lineages are RNU6-741P, MIR4529, and RRM1. Each is linked with NEUROD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEUROD1-to-partner and partner-to-NEUROD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-741P grouped by NEUROD1-low versus NEUROD1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD1→partner) and Y-score (partner→NEUROD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-741P →	+0.161	+5.535	<.001	<.001	3	4
SKCM	MIR4529 →	+0.124	+3.784	<.001	.009	3	3
UCEC	RRM1 →	+0.645	+1.925	.003	.005	3	3
UCEC	UHRF1 →	+0.740	+2.818	.001	<.001	3	2
READ	RPL7L1P12 →	+0.207	+4.202	<.001	.008	3	2
READ	NICN2P →	+0.193	+4.533	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,114 associations by consensus.

RNU6-741P by NEUROD1 expression — LUAD

Explore this box plot interactively →