NEUROD1

Across TCGA cell cohorts, NEUROD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 544 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NEUROD1-associated GO terms across cancer lineages are Amacrine cell differentiation, Noradrenergic neuron development, and Sodium-dependent phosphate transport. Each is linked with NEUROD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEUROD1-to-partner and partner-to-NEUROD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amacrine cell differentiation grouped by NEUROD1-low versus NEUROD1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROD1→partner) and Y-score (partner→NEUROD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Amacrine cell differentiation →	+1.040	+3.821	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Noradrenergic neuron development →	+0.442	+0.053	<.001	.001	2	4
LUNG_SCLC	Sodium-dependent phosphate transport →	+1.055	+2.866	<.001	<.001	3	3
LUNG_SCLC	Regulation of necroptotic process →	-0.096	-3.963	.005	.002	3	3
LUNG_SCLC	Adenylate cyclase-inhibiting dopamine receptor signaling pathway →	-0.253	-4.238	.005	<.001	3	3
BREAST	Negative regulation of DNA binding →	+0.110	+0.014	.004	.004	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 544 associations by consensus.

Amacrine cell differentiation by NEUROD1 expression — LUNG_SCLC

Explore this box plot interactively →