NEURL1

Across TCGA patient cohorts, NEURL1 mutation is significantly associated with the RNA expression of many other genes, with 906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEURL1-associated genes across cancer lineages are RNU6-222P, RNU6-919P, and RN7SL339P. Each is linked with NEURL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEURL1-to-partner and partner-to-NEURL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-222P grouped by NEURL1-low versus NEURL1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEURL1→partner) and Y-score (partner→NEURL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-222P →	+0.623	+5.008	<.001	.004	3	3
LIHC	RNU6-919P →	+0.301	+4.647	<.001	.007	3	2
LIHC	RN7SL339P →	+0.122	+4.758	<.001	.006	3	2
UCEC	GUF1 →	+0.462	+3.346	.007	.005	3	2
UCEC	REEP4 →	+0.558	+3.354	.004	.005	3	2
UCEC	GPS1 →	+0.442	+3.376	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 906 associations by consensus.

RNU6-222P by NEURL1 expression — LIHC

Explore this box plot interactively →