NEURL1

Across TCGA pan-cancer cohorts, NEURL1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NEURL1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where NEURL1 RNA is repressed in tumor relative to normal tissue. In most cancer types NEURL1 is over-expressed in tumor, although a few such as KIRP and COAD show the opposite, repressed pattern.

KIRP, COAD, and KICH are the cancer types where NEURL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NEURL1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	−0.887	<.001	11	view →
COAD	Female	III,IV	−2.776	<.001	10	view →
KICH	Female	II,III,IV	+3.235	<.001	8	view →
BLCA	All	III,IV	−2.094	<.001	8	view →
KIRC	Male	II,III,IV	−0.448	<.001	7	view →
UCEC	All	All	−2.446	<.001	6	view →
BRCA	All	III,IV	+1.749	<.001	6	view →
LUSC	All	II,III,IV	+1.447	<.001	6	view →
THCA	Female	All	+0.329	<.001	5	view →
PRAD	All	All	−0.400	<.001	2	view →
CHOL	All	All	+1.210	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

NEURL1–KIRP

Open the KIRP breakdown →