Across TCGA patient cohorts, NEU4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,234 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEU4-associated genes across cancer lineages are SNRPD3, GGT1, and ESS2. Each is linked with NEU4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEU4-to-partner and partner-to-NEU4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU4→partner) and Y-score (partner→NEU4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.521	+0.709	.005	.005	3	1
GBM	GGT1 →	+0.285	+0.803	.001	<.001	3	1
GBM	ESS2 →	+0.378	+0.720	<.001	<.001	3	1
GBM	HIRA →	+0.323	+0.606	.002	.001	3	1
GBM	SEZ6L →	+1.635	+0.587	.005	.005	3	1
GBM	PATZ1 →	+0.515	+0.706	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,234 associations by consensus.

Exploration

NEU4 survival (RNA) · tumor vs normal (RNA) · all NEU4 data types