Across TCGA patient cohorts, NEU4 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEU4-associated genes across cancer lineages are Bap1-c-4, FASN, and GATA6. Each is linked with NEU4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEU4-to-partner and partner-to-NEU4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU4→partner) and Y-score (partner→NEU4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bap1-c-4 →	+0.304	+3.000	.044	.035	3	2
UCEC	FASN →	+0.789	+3.000	<.001	.037	3	1
UCEC	GATA6 →	-0.179	-2.992	.045	.036	3	1
UCEC	Heregulin →	-0.201	-2.986	.004	.035	3	1
UCEC	Caspase-8 →	-0.343	-3.000	.018	.037	3	1
UCEC	Collagen-VI →	-0.296	-3.000	.012	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

NEU4 survival (RNA) · tumor vs normal (RNA) · all NEU4 data types