NEU2

Across TCGA patient cohorts, NEU2 mutation is significantly associated with the RNA expression of many other genes, with 3,661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEU2-associated genes across cancer lineages are ATAD5, KIF18B, and H1-0. Each is linked with NEU2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEU2-to-partner and partner-to-NEU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATAD5 grouped by NEU2-low versus NEU2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU2→partner) and Y-score (partner→NEU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATAD5 →	+0.675	+3.469	<.001	.002	3	3
UCEC	KIF18B →	+0.877	+2.343	<.001	<.001	3	3
SKCM	H1-0 →	+0.846	+3.710	.002	<.001	3	3
UCEC	UTP18 →	+0.539	+3.721	.001	<.001	3	3
LUSC	RNU6-916P →	+0.424	+4.978	<.001	<.001	3	3
SKCM	SNHG1 →	+0.764	+2.341	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,661 associations by consensus.

ATAD5 by NEU2 expression — SKCM

Explore this box plot interactively →