NEU2

Across TCGA pan-cancer cohorts, NEU2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NEU2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NEU2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NEU2 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

LUSC and READ are the cancer types where NEU2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NEU2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.092	.004	4	view →
READ	All	II,III,IV	−0.045	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

NEU2–LUSC

Open the LUSC breakdown →