Across TCGA patient cohorts, NEU1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,682 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NEU1-associated genes across cancer lineages are THG1L, RPN2, and PDIA4. Each is linked with NEU1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEU1-to-partner and partner-to-NEU1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU1→partner) and Y-score (partner→NEU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THG1L →	-0.638	-0.233	.002	.003	3	4
LSCC	RPN2 →	+0.408	+0.244	<.001	<.001	3	4
CCRCC	PDIA4 →	+0.408	+0.210	<.001	<.001	3	4
LSCC	P4HB →	+0.433	+0.239	<.001	<.001	3	4
GBM	HSPA5 →	+0.571	+0.265	<.001	<.001	3	4
GBM	FNDC3B →	+0.598	+0.338	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,682 associations by consensus.

Exploration

NEU1 survival (RNA) · tumor vs normal (RNA) · all NEU1 data types