NETO2

Across TCGA patient cohorts, NETO2 mutation is significantly associated with the RNA expression of many other genes, with 2,026 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NETO2-associated genes across cancer lineages are DNAJC9, NCKIPSD, and UBBP3. Each is linked with NETO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NETO2-to-partner and partner-to-NETO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJC9 grouped by NETO2-low versus NETO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NETO2→partner) and Y-score (partner→NETO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAJC9 →	+0.694	+2.684	<.001	<.001	3	2
UCEC	NCKIPSD →	+0.511	+2.673	<.001	<.001	3	2
COAD	UBBP3 →	+0.737	+3.875	<.001	.004	3	2
UCEC	IMP3P2 →	+0.193	+1.592	<.001	.009	3	2
UCEC	TRDV3 →	+0.308	+1.647	<.001	.009	3	2
UCEC	SNAI3-AS1 →	+0.313	+2.716	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,026 associations by consensus.

DNAJC9 by NETO2 expression — UCEC

Explore this box plot interactively →