NETO1

Across TCGA patient cohorts, NETO1 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NETO1-associated genes across cancer lineages are Cyclin-B1, PCNA, and 4E-BP1. Each is linked with NETO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NETO1-to-partner and partner-to-NETO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by NETO1-low versus NETO1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NETO1→partner) and Y-score (partner→NETO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Cyclin-B1 →	+0.661	+3.459	.003	.005	2	6
COAD	PCNA →	+0.361	+3.012	<.001	.018	3	4
LUAD	4E-BP1 →	+0.468	+3.459	<.001	.004	3	4
UCEC	TFRC →	+0.371	+2.000	.022	.029	3	4
LUAD	FoxM1 →	+0.343	+2.713	<.001	.003	3	3
COAD	GAPDH →	+0.575	+3.000	.006	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Cyclin-B1 by NETO1 expression — COAD

Explore this box plot interactively →