NEO1

Across TCGA cell cohorts, NEO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,999 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEO1-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of nucleotide-excision repair. Each is linked with NEO1 in more than 13 cancer types. Because this analysis shows association rather than direction, both NEO1-to-partner and partner-to-NEO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by NEO1-low versus NEO1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEO1→partner) and Y-score (partner→NEO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin formation →	+0.059	+1.710	<.001	<.001	3	14
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.097	+1.751	.002	.003	3	13
OVARY	Regulation of nucleotide-excision repair →	+0.115	+1.730	<.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.079	+2.006	<.001	<.001	3	12
OVARY	Mitotic cytokinesis →	+0.067	+1.746	.004	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.053	+1.143	.003	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,999 associations by consensus.

Heterochromatin formation by NEO1 expression — OVARY

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