NENF

Across TCGA patient cohorts, NENF mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NENF-associated genes across cancer lineages are MIR518A1, MIR7155, and ACTRT2. Each is linked with NENF in more than 1 cancer types. Because this analysis shows association rather than direction, both NENF-to-partner and partner-to-NENF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR518A1 grouped by NENF-low versus NENF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NENF→partner) and Y-score (partner→NENF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR518A1 →	+0.319	+3.997	<.001	.009	3	2
UCEC	MIR7155 →	+0.610	+3.957	<.001	.002	3	1
SKCM	ACTRT2 →	+0.039	+5.408	<.001	.002	3	1
SKCM	RNU1-49P →	+0.197	+5.408	<.001	.002	3	1
SKCM	LINC01445 →	+0.031	+4.614	.003	.006	3	1
UCEC	TRAJ21 →	+0.759	+3.351	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MIR518A1 by NENF expression — UCEC

Explore this box plot interactively →