NENF

Across TCGA cell cohorts, NENF RNA expression is significantly associated with the go_rna of many other GO terms, with 2,801 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NENF-associated GO terms across cancer lineages are Porphyrin-containing compound metabolic process, Heme metabolic process, and Pigment metabolic process. Each is linked with NENF in more than 9 cancer types. Because this analysis shows association rather than direction, both NENF-to-partner and partner-to-NENF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Porphyrin-containing compound metabolic process grouped by NENF-low versus NENF-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NENF→partner) and Y-score (partner→NENF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Porphyrin-containing compound metabolic process →	+0.079	+0.896	.001	.002	2	10
PANCREAS	Heme metabolic process →	+0.089	+0.733	.003	.001	2	9
PANCREAS	Pigment metabolic process →	+0.087	+0.743	.003	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Tetrapyrrole biosynthetic process →	+0.075	+0.813	.002	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Porphyrin-containing compound biosynthetic process →	+0.075	+0.813	.002	.002	3	8
BONE	Geranyl diphosphate metabolic process →	+0.123	+0.828	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,801 associations by consensus.

Porphyrin-containing compound metabolic process by NENF expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →