Across TCGA patient cohorts, NEMP2 mutation is significantly associated with the RNA expression of many other genes, with 431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEMP2-associated genes across cancer lineages are ESS2, TOMM22, and RTCB. Each is linked with NEMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEMP2-to-partner and partner-to-NEMP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMP2→partner) and Y-score (partner→NEMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ESS2 →	+0.410	+3.332	.002	.005	3	1
UCEC	TOMM22 →	+0.502	+3.202	.009	.009	3	1
UCEC	RTCB →	+0.631	+3.375	.005	.005	3	1
UCEC	MRPS31 →	+0.547	+3.332	.002	.005	3	1
UCEC	POLR2C →	+0.541	+3.332	.006	.005	3	1
UCEC	COG4 →	+0.470	+3.218	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 431 associations by consensus.

Exploration

NEMP2 survival (RNA) · tumor vs normal (RNA) · all NEMP2 data types