Across TCGA patient cohorts, NEMP2 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEMP2-associated genes across cancer lineages are Notch1, VHL, and P-Cadherin. Each is linked with NEMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEMP2-to-partner and partner-to-NEMP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEMP2→partner) and Y-score (partner→NEMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.267	+3.009	<.001	.019	3	1
UCEC	VHL →	-0.892	-3.169	.016	.020	3	1
UCEC	P-Cadherin →	-0.216	-2.990	.006	.036	2	1
UCEC	Rab25 →	-0.421	-3.169	.020	.020	2	1
UCEC	c-Jun_pS73 →	-0.197	-2.990	.023	.036	2	1
UCEC	JNK_pT183_Y185 →	-0.250	-3.156	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

NEMP2 survival (RNA) · tumor vs normal (RNA) · all NEMP2 data types