NELL1

Across TCGA patient cohorts, NELL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,369 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NELL1-associated genes across cancer lineages are CA14, GDAP1L1, and ANK3. Each is linked with NELL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NELL1-to-partner and partner-to-NELL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NELL1 versus CA14 in GBM, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELL1→partner) and Y-score (partner→NELL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CA14 →	+1.531	+0.833	.001	.001	3	2
GBM	GDAP1L1 →	+1.466	+0.726	.002	<.001	3	2
GBM	ANK3 →	+1.705	+0.733	.001	.002	3	2
GBM	CELF5 →	+1.471	+0.612	.007	.001	3	2
GBM	ZNF565 →	+0.448	+0.761	.008	.002	3	2
LUAD	RNA5SP336 →	+2.089	+1.625	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,369 associations by consensus.

NELL1 vs CA14 — GBM

Explore this scatter interactively →