NEK2

Across TCGA patient cohorts, NEK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NEK2-associated proteins across cancer lineages are RFC1_T506, RFC4, and RIF1. Each is linked with NEK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NEK2-to-partner and partner-to-NEK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK2 versus RFC1_T506 in LUAD, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK2→partner) and Y-score (partner→NEK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RFC1_T506 →	+1.381	+1.663	<.001	<.001	3	10
LSCC	RFC4 →	+0.472	+0.930	<.001	<.001	3	10
BRCA	RIF1 →	+0.540	+1.210	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.302	+1.503	<.001	<.001	3	10
LUAD	RRM2 →	+0.957	+1.628	<.001	<.001	3	10
LUAD	RRP36_S73 →	+0.848	+1.287	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,892 associations by consensus.

NEK2 vs RFC1_T506 — LUAD

Explore this scatter interactively →