NEK11

Across TCGA patient cohorts, NEK11 protein abundance is significantly associated with the RNA expression of many other genes, with 2,930 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEK11-associated genes across cancer lineages are NME5, ENKUR, and FAM81B. Each is linked with NEK11 in more than 2 cancer types. Because this analysis shows association rather than direction, both NEK11-to-partner and partner-to-NEK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK11 versus NME5 in UCEC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK11→partner) and Y-score (partner→NEK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NME5 →	+1.831	+0.700	<.001	<.001	3	3
UCEC	ENKUR →	+2.105	+0.561	<.001	.004	3	3
UCEC	FAM81B →	+1.983	+0.541	.001	.009	3	3
UCEC	RSPH1 →	+1.922	+0.614	<.001	.001	3	3
UCEC	CABCOCO1 →	+2.106	+0.531	<.001	.007	3	3
UCEC	CFAP43 →	+2.182	+0.654	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,930 associations by consensus.

NEK11 vs NME5 — UCEC

Explore this scatter interactively →