NEK1

Across TCGA patient cohorts, NEK1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,197 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NEK1-associated genes across cancer lineages are LAMP5, ABCA9, and UFSP2. Each is linked with NEK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NEK1-to-partner and partner-to-NEK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK1 versus LAMP5 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK1→partner) and Y-score (partner→NEK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LAMP5 →	+1.942	+0.320	<.001	.003	3	6
BRCA	ABCA9 →	+1.157	+0.272	<.001	<.001	3	6
OV	UFSP2 →	+0.754	+0.354	<.001	<.001	3	6
UCEC	OLFML3 →	+1.420	+0.304	<.001	<.001	3	5
UCEC	GSTM5 →	+0.735	+0.296	.003	<.001	3	5
OV	LRRC4C →	+0.797	+0.389	.003	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,197 associations by consensus.

NEK1 vs LAMP5 — OV

Explore this scatter interactively →