NEK1

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NEK1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,656 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEK1-associated genes across cancer lineages are CLCN3, KIAA1109, and CEP44. Each is linked with NEK1 in more than 17 cancer types. Because this analysis shows association rather than direction, both NEK1-to-partner and partner-to-NEK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEK1 versus CLCN3 in BONE, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK1→partner) and Y-score (partner→NEK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONECLCN3 →+1.283+1.000<.001<.001317
BONEKIAA1109 →+0.987+0.786.002.001218
LUNG_NSCLC_LUSCCEP44 →+1.137+1.115<.001<.001316
LIVERTRAPPC11 →+1.014+1.030<.001<.001217
BLOOD_LymphomaLARP7 →+1.001+0.896<.001<.001316
LUNG_NSCLC_LUSCRAB23 →+1.329+0.855.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,656 associations by consensus.

NEK1 vs CLCN3 — BONE

Per-sample scatter of NEK1 vs CLCN3 in BONE (Pearson r = 0.71).

Explore this scatter interactively →

Exploration