NEIL3

Across TCGA patient cohorts, NEIL3 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEIL3-associated proteins across cancer lineages are C6orf89, COMT_S267, and IGSF3. Each is linked with NEIL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEIL3-to-partner and partner-to-NEIL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEIL3 versus C6orf89 in CCRCC, with a Pearson correlation of 0.96.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEIL3→partner) and Y-score (partner→NEIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	C6orf89 →	+0.447	+1.030	<.001	<.001	3	1
CCRCC	COMT_S267 →	-0.384	-1.030	.001	<.001	3	1
CCRCC	IGSF3 →	+0.856	+1.190	<.001	.001	3	1
CCRCC	LAD1_S177 →	+2.570	+1.189	<.001	.001	3	1
CCRCC	MICALL1 →	-0.413	-1.189	<.001	.001	3	1
CCRCC	SEMA4D_S857 →	+0.377	+1.030	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,309 associations by consensus.

NEIL3 vs C6orf89 — CCRCC

Explore this scatter interactively →