NEIL3

Across TCGA cell cohorts, NEIL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,375 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEIL3-associated GO terms across cancer lineages are Interstrand cross-link repair, Depurination, and Nuclear division. Each is linked with NEIL3 in more than 18 cancer types. Because this analysis shows association rather than direction, both NEIL3-to-partner and partner-to-NEIL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by NEIL3-low versus NEIL3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEIL3→partner) and Y-score (partner→NEIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Interstrand cross-link repair →	+0.102	+1.361	<.001	<.001	3	19
LIVER	Depurination →	+0.248	+2.086	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.101	+1.589	<.001	<.001	3	19
BREAST	Regulation of G2/M transition of mitotic cell cycle →	+0.096	+1.426	<.001	<.001	3	18
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.114	+0.968	<.001	<.001	3	18
STOMACH	Mitochondrial DNA repair →	+0.126	+1.045	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,375 associations by consensus.

Interstrand cross-link repair by NEIL3 expression — PANCREAS

Explore this box plot interactively →