NEIL2

Across TCGA patient cohorts, NEIL2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,595 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEIL2-associated genes across cancer lineages are MCPH1, CNOT7, and PLAU. Each is linked with NEIL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NEIL2-to-partner and partner-to-NEIL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEIL2 versus MCPH1 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEIL2→partner) and Y-score (partner→NEIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MCPH1 →	+0.595	+0.500	<.001	<.001	3	6
UCEC	CNOT7 →	+0.399	+0.217	.002	.001	3	6
OV	PLAU →	-1.312	-0.344	<.001	.001	3	5
BRCA	HMBOX1 →	+0.549	+0.486	<.001	<.001	3	5
BRCA	FAM160B2 →	+0.550	+0.435	.001	<.001	3	5
HNSC	WRN →	+0.486	+0.346	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,595 associations by consensus.

NEIL2 vs MCPH1 — BRCA

Explore this scatter interactively →