NEIL1

Across TCGA pan-cancer cohorts, NEIL1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NEIL1 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NEIL1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NEIL1 expression acts as an unfavorable survival marker.

PDAC, LSCC, and LUAD are the cancer types where NEIL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.632	0.926	.013	6	view →
LSCC	OS	Median	III,IV	0.527	0.928	.042	4	view →
LUAD	DFS	Median	All	0.844	1.000	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NEIL1–PDAC (DFS)

Open the PDAC breakdown →