NEIL1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NEIL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEIL1-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Flagellated sperm motility, and Sperm motility. Each is linked with NEIL1 in more than 14 cancer types. Because this analysis shows association rather than direction, both NEIL1-to-partner and partner-to-NEIL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by NEIL1-low versus NEIL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEIL1→partner) and Y-score (partner→NEIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCilium or flagellum-dependent cell motility →-0.099-1.057<.001<.001315
UPPER_AERODIGESTIVE_TRACTFlagellated sperm motility →-0.124-1.412<.001<.001315
UPPER_AERODIGESTIVE_TRACTSperm motility →-0.124-1.412<.001<.001315
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.099-1.057<.001<.001315
URINARY_TRACTCilium movement involved in cell motility →-0.115-1.658<.001<.001315
OESOPHAGUSCo-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →+0.144+2.064.003<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Cilium or flagellum-dependent cell motility by NEIL1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Cilium or flagellum-dependent cell motility in NEIL1-low vs NEIL1-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration