NEFM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NEFM RNA expression is significantly associated with the protein abundance of many other proteins, with 14,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEFM-associated proteins across cancer lineages are MAP1LC3A, SGCD, and CACNA2D1. Each is linked with NEFM in more than 3 cancer types. Because this analysis shows association rather than direction, both NEFM-to-partner and partner-to-NEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEFM versus MAP1LC3A in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFM→partner) and Y-score (partner→NEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMAP1LC3A →+0.602+0.389.001.00834
BRCASGCD →+0.872+0.314<.001<.00134
GBMCACNA2D1 →+0.622+0.964<.001<.00134
UCECATL1 →+0.672+1.479<.001<.00134
UCECPTGES3 →-0.262-1.222.002<.00133
GBMPUS7_S90 →-0.751-1.435.003.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,571 associations by consensus.

NEFM vs MAP1LC3A — LSCC

Per-sample scatter of NEFM vs MAP1LC3A in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration