NEFM

Across TCGA patient cohorts, NEFM protein abundance is significantly associated with the RNA expression of many other genes, with 6,021 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEFM-associated genes across cancer lineages are RELN, GFRA1, and PRR18. Each is linked with NEFM in more than 3 cancer types. Because this analysis shows association rather than direction, both NEFM-to-partner and partner-to-NEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEFM versus RELN in LUAD, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFM→partner) and Y-score (partner→NEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RELN →	+1.130	+1.160	.007	.003	3	4
CCRCC	GFRA1 →	+1.745	+1.008	.002	.002	3	4
GBM	PRR18 →	+1.057	+1.133	<.001	<.001	3	3
LUAD	TSPYL5 →	+1.911	+1.464	.001	.002	3	3
GBM	PGAP4 →	+1.377	+1.375	<.001	<.001	3	3
PDAC	CXCL12 →	+1.073	+0.950	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,021 associations by consensus.

NEFM vs RELN — LUAD

Explore this scatter interactively →