NEFM

Across TCGA patient cohorts, NEFM protein abundance is significantly associated with the protein abundance of many other proteins, with 20,531 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEFM-associated proteins across cancer lineages are NEFM_S633, HSPA12B, and NEFL. Each is linked with NEFM in more than 4 cancer types. Because this analysis shows association rather than direction, both NEFM-to-partner and partner-to-NEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEFM versus NEFM_S633 in PDAC, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFM→partner) and Y-score (partner→NEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NEFM_S633 →	+1.861	+0.866	<.001	<.001	3	5
UCEC	HSPA12B →	+0.608	+0.677	<.001	<.001	3	4
HNSC	NEFL →	+1.454	+1.349	<.001	<.001	3	4
UCEC	COG5 →	-0.247	-0.549	<.001	<.001	3	4
GBM	DARS1 →	-0.174	-0.876	<.001	<.001	3	4
HNSC	LDB3 →	+0.965	+0.822	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,531 associations by consensus.

NEFM vs NEFM_S633 — PDAC

Explore this scatter interactively →