NEFM

Across TCGA cell cohorts, NEFM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,496 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEFM-associated GO terms across cancer lineages are Neurofilament bundle assembly, Postsynaptic intermediate filament cytoskeleton organization, and Positive regulation of telomere maintenance via telomere lengthening. Each is linked with NEFM in more than 10 cancer types. Because this analysis shows association rather than direction, both NEFM-to-partner and partner-to-NEFM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurofilament bundle assembly grouped by NEFM-low versus NEFM-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFM→partner) and Y-score (partner→NEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Neurofilament bundle assembly →	+1.696	+2.116	<.001	<.001	3	11
BONE	Postsynaptic intermediate filament cytoskeleton organization →	+1.213	+3.032	.003	.009	3	7
SKIN	Positive regulation of telomere maintenance via telomere lengthening →	+0.053	+1.114	.007	.002	3	7
SKIN	Cytoplasmic translational initiation →	+0.082	+1.015	<.001	<.001	3	7
LUNG_SCLC	Translational initiation →	+0.071	+2.476	.004	.002	3	7
SKIN	Protein-RNA complex assembly →	+0.057	+1.154	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,496 associations by consensus.

Neurofilament bundle assembly by NEFM expression — URINARY_TRACT

Explore this box plot interactively →