NECTIN3

Across TCGA cell cohorts, NECTIN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,789 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NECTIN3-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Actin filament fragmentation. Each is linked with NECTIN3 in more than 10 cancer types. Because this analysis shows association rather than direction, both NECTIN3-to-partner and partner-to-NECTIN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by NECTIN3-low versus NECTIN3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NECTIN3→partner) and Y-score (partner→NECTIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Transport of virus →	+0.159	+2.033	.001	.001	3	11
BREAST	Intracellular transport of virus →	+0.159	+2.033	.001	.001	3	11
BONE	Actin filament fragmentation →	+0.116	+1.797	<.001	<.001	3	10
URINARY_TRACT	PML body organization →	+0.201	+1.572	<.001	.007	2	11
BONE	Regulation of intracellular transport →	+0.071	+2.080	.001	<.001	3	10
SOFT_TISSUE	Interleukin-11-mediated signaling pathway →	+0.168	+2.411	.002	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,789 associations by consensus.

Transport of virus by NECTIN3 expression — BREAST

Explore this box plot interactively →