NECAB3

Across TCGA patient cohorts, NECAB3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,602 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NECAB3-associated genes across cancer lineages are PDIA3, SIX4, and PTK6. Each is linked with NECAB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NECAB3-to-partner and partner-to-NECAB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECAB3 versus PDIA3 in LSCC, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NECAB3→partner) and Y-score (partner→NECAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDIA3 →	-0.742	-0.146	.004	.009	3	2
LSCC	SIX4 →	-0.959	-0.145	.005	.009	3	1
LSCC	PTK6 →	-1.288	-0.146	.002	.009	3	1
LSCC	ZNF419 →	-0.974	-0.145	.001	.009	3	1
LSCC	DMAC2 →	-0.519	-0.146	<.001	.009	3	1
LSCC	ZNF574 →	-0.525	-0.145	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,602 associations by consensus.

NECAB3 vs PDIA3 — LSCC

Explore this scatter interactively →