NECAB3

Across TCGA cell cohorts, NECAB3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NECAB3-associated genes across cancer lineages are MYOD1, FCN2, and TNP1. Each is linked with NECAB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NECAB3-to-partner and partner-to-NECAB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by NECAB3-low versus NECAB3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NECAB3→partner) and Y-score (partner→NECAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOD1 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	FCN2 →	+0.018	+5.201	<.001	.006	3	1
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF831 →	+0.010	+4.273	.004	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.182	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MYOD1 by NECAB3 expression — BLOOD_Leukemia

Explore this box plot interactively →