NEBL

Across TCGA cell cohorts, NEBL mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NEBL-associated genes across cancer lineages are GYS2, TMEM252, and DIPK1C. Each is linked with NEBL in more than 1 cancer types. Because this analysis shows association rather than direction, both NEBL-to-partner and partner-to-NEBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GYS2 grouped by NEBL-low versus NEBL-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEBL→partner) and Y-score (partner→NEBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	GYS2 →	+0.193	+4.237	<.001	.006	3	1
PANCREAS	TMEM252 →	+0.016	+4.786	<.001	.001	3	1
PANCREAS	DIPK1C →	+0.017	+4.491	.008	.003	3	1
BONE	IFNA13 →	+0.043	+5.169	<.001	.004	3	1
BLOOD_Lymphoma	REG3G →	+0.044	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

GYS2 by NEBL expression — PANCREAS

Explore this box plot interactively →